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New paper describes genetic connections between biological rhythms, timing of feeding and insulin sensitivity

Author: William G. Gilroy

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A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

Obesity and diabetes have reached epidemic levels and are responsible for increased morbidity and mortality throughout the world. Furthermore, the incidence of metabolic disease is significantly elevated in shift-work personnel, revealing an important link between the circadian clock, the sleep-wake cycle, time-of-day feeding and metabolism.

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