Uncovering a new pathway to halting metastasis
Metastasis, the process by which cancer cells leave the primary tumor and spread to other sites in the body, is responsible for more than 90 percent of cancer deaths. Thus, there is a significant need to improve the therapeutic options for patients who suffer from metastatic disease. New research from the laboratory of Zachary T. Schafer, associate professor in the Department of Biological Sciences, Coleman Foundation Collegiate Chair of Cancer Biology and researcher in the Harper Cancer Research Institute, could lead to these new therapies.
Reinterpreting the fossil record on jaws
Scientists use the fossil record to make judgments on the physiology and behavior of species. But are those interpretations correct? New research from a team of researchers led by Matthew Ravosa, professor of biology and concurrent professor of both aerospace and mechanical engineering and anthropology, puts into question how we interpret the behavior of extinct organisms from their fossil remains, and the greater role of plasticity — or the adaptive fine-tuning of the link between anatomy and behavior — in determining evolution diversity.