Xuemin Lu

Academic Interests:

I am interested in leveraging metabolic and dietary interventions to modulate disease microenvironments, enhance cancer immunotherapy, and reverse immunosuppression within the tumor microenvironment. I am also investigating diet-regulated epigenetic therapies and mitochondrial bioenergetics to counter transcriptional silencing and cellular dysfunction in neurodegenerative diseases like Friedreich’s Ataxia. My current and future projects incorporate organoid cultures and mitochondrial functional assays to identify novel therapeutic targets at the intersection of metabolism, epigenetics, and disease progression.

Biography:

• Associate Professor of the Practice, Department of Biological Sciences
• Assistant Teaching Professor, Department of Biological Sciences, University of Notre Dame
• Undergrad Research Director, College of Science, University of Notre Dame
• Product Lead, Cardiovascular Division, Admera Health LLC.
• Senior Clinical Scientist & Team Leader, Clinical Services, Admera Health LLC.
• Research Associate, Medical Genetics Laboratory, Baylor College of Medicine
• Ruth L. Kirschstein National Research Fellow, Baylor College of Medicine
• Technology Transfer and Business Development Intern, Licensing Group, Baylor College of Medicine
• Postdoc Associate, Department of Biology, Massachusetts Institute of Technology
• Ph.D. Molecular Biology, Princeton University
• B.S. Math & Physics, Tsinghua University, China

Undergrad Research in College of Science

Primary Research Areas:

Cancer
Cellular & Molecular Biology
Development & Regeneration
Genetics and Genomics