Researchers at the University of Notre Dame have outlined the delivery mechanism tumor cells use to move nucleic acids into small sacs shed from their surfaces — information that is eventually shared with other cells within the tumor, causing the cancer to spread.
Within the next 80 years, global food demand is expected to increase sharply to meet the needs of a projected world population topping 11 billion. The increase in agriculture will likely influence human infectious diseases, which in turn may affect food production and distribution, according to a review paper by University of Notre Dame biologist Jason Rohr and collaborators.
A major outbreak of dengue fever in southern China in 2014 may have been caused by more than just high temperatures, numbers of mosquitoes, or imported cases from Southeast Asia. Despite previous studies that point to these specific reasons for the outbreak that affected almost 40,000 people, a new study from the University of Notre Dame shows there likely were other factors involved as well.
Finding solutions for worldwide shortages propels new University of Notre Dame biology professor Jason Rohr to find unique ways to research some of the most pressing issues.
These include food shortages. Energy shortages. Even “shortages” of amphibians because of disease. Rohr, the Ludmilla F., Stephen J., and Robert T. Galla College Professor of Biological Sciences, completes research in areas that span the intersection of wildlife and human health.
New research from the University of Notre Dame suggests that structures released by the infected cells may be used in tandem with antibiotics to boost the body’s immune system, helping fight off the disease.
New research from Notre Dame could lead to regenerative therapies for people with injuries to their brachial plexus, a group of nerves that starts at the spinal cord and goes into the arm.
Siyuan Zhang, the Dee Associate Professor of Biological Sciences who is also affiliated with the Harper Cancer Research Institute, landed a nearly $1.1 million Breast Cancer Research Program Breakthrough Award through the Department of Defense in August.
Xin Lu, the John M. and Mary Jo Boler Assistant Professor of biology, was awarded a 2018 Susan G. Komen research grant to identify potential new therapies for treating metastatic breast cancer.
From poster sessions to presentations, the College of Science Joint Annual Meeting (COS-JAM) on May 4, 2018, showcased the depth of undergraduate research completed by students within the fields of science and engineering.
Eighty-nine students presented posters and 23 gave oral presentations during sessions held in the Jordan Hall of Science. Hundreds of students, professors and others met with the presenters to learn more about their work.
Presenting to peers at COS-JAM is a low-stakes way for students to develop experience sharing their research. It is a skill they will use as they advance to graduate school and the workplace. “Scientific communication, like presentations at COS-JAM, is an integral part of research,” said Xuemin Lu, undergraduate research director for the College of Science and assistant teaching professor in the Department of Biological Sciences.
A blend of dedication to the community and a joyful work ethic landed two science professors in the spotlight as they were inducted into the 2018 Michiana Forty under 40 class.
The inductees from the College of Science were Nancy Michael, assistant teaching professor and director of undergraduate studies, Neuroscience and Behavior; and Jenifer Prosperi, adjunct assistant professor in the Department of Biological Sciences at Notre Dame and member of Harper Cancer Research Institute, as well as assistant professor of biochemistry and molecular biology, Indiana University School of Medicine–South Bend. A third inductee from Notre Dame was Regan Jones, the University’s director for military and veterans affairs.
Tiny proteins found in the genomes of some types of bacteria are effective weapons against a wide range of other bacteria, opening the door for the development of new therapies in the age of antibiotic resistance, according to new research at the University of Notre Dame.
To stop the spread of cancer, cancer cells must die. Unfortunately, many types of cancer cells seem to use innate mechanisms that block cancer cell death, therefore allowing the cancer to metastasize. While seeking to further understand cancer cell death, researchers at the University of Notre Dame discovered that the activation of a specific enzyme may help suppress the spread of tumors.
The findings, published in Nature Cell Biology, demonstrate that the enzyme RIPK1 decreases the number of mitochondria in a cell. This loss of mitochondria leads to oxidative stress that can potentially kill cancer cells, though researchers speculate the cancer cells could find ways to shut down this effect.
Notre Dame’s first Life Sciences Symposium brought together leading biomedical researchers for a day of lectures and poster presentations, drawing about 200 students and scientists from across the area.
The event, “Bridging the Gap from Bench to Bedside,” was held Oct. 11, 2017, at the Morris Inn and was organized and hosted by students in the Department of Biological Sciences graduate program. Attendees came from Indiana, Michigan, Illinois, and Ohio to hear researchers present topics from stem cells in cancer to neurobiology and regeneration.
Research took precedence over relaxation for several College of Science students this summer who spent 10 weeks completing undergraduate research projects at MD Anderson Cancer Center in Houston, Texas. Two students from biological sciences, Colin Sheehan and Shane Davitt, were among the participants.
The University of Notre Dame Summer Undergraduate Research Program at MD Anderson is a competitive program designed for outstanding and highly motivated undergraduate students interested in pursuing a career in cancer research. Students participated in various types of research in different labs, attended lectures and presentations, and collaborated with others as they fostered their interest in a research career path.
From studying Fragile X Syndrome to understanding algorithms for artificial intelligence, 47 students participated in a summer’s worth of research, thanks to the College of Science Summer Undergraduate Research Fellowships (SURF).
The program is made possible through donors and in collaboration with the Center of Undergraduate Scholarly Engagement, Indiana University School of Medicine–South Bend, and the Glynn Family Honors program.
David J. Veselik, director of undergraduate studies and associate teaching professor in the department of biological sciences, was one of three recipients of the Dockweiler Awards for the 2016–2017 academic year.
Veselik is the coordinator for the cell biology laboratory, as well as the biology club advisor. He has taught upper level cell biology labs and lectures. With his guidance, students have participated in several initiatives, including networking with the career center, vertical peer mentoring, lab shadowing and alumni mentoring.