Advancing Evidence for the Global Implementation of Spatial Repellents(AEGIS)

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Funded by Unitaid, the project is evaluating a novel vector control product, ENVELOPE, with the potential to contribute to dramatic gains in malaria and Aedes-borne virus control in a variety of development contexts. The goal of the project is to generate evidence on a SR product as an efficacious and cost-effective vector control tool as a complement to existing vector control strategies. The evidence is meant to provide data on feasibility, impact and safety that can be used to endorse a policy recommendation by WHO for SRs as a complementary tool for vector control. This will be achieved through tree randomized-cluster trials (Kenya, Mali and Sri Lanka) and an operational study in Uganda. In Sri Lanka, researchers will evaluate effectiveness against Aedes-borne virus infections, primarily dengue. They will evaluate protection against new human malaria infections to address residual transmission in Kenya. In the operational site, Uganda, they will evaluate effectiveness against malaria infections in rural African environments linked to displaced persons.

Principal Investigator: John P. Grieco

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