Reinterpreting the fossil record on jaws
Scientists use the fossil record to make judgments on the physiology and behavior of species. But are those interpretations correct? New research from a team of researchers led by Matthew Ravosa, professor of biology and concurrent professor of both aerospace and mechanical engineering and anthropology, puts into question how we interpret the behavior of extinct organisms from their fossil remains, and the greater role of plasticity — or the adaptive fine-tuning of the link between anatomy and behavior — in determining evolution diversity.
Holding the Key to Affordable Biotherapeutics
Malcolm Fraser Jr., the University of Notre Dame’s Rev. Julius A. Nieuwland, C.S.C., Professor of Biological Sciences, is conducting research that utilizes the silkworm caterpillar’s silk gland to conduct mammalian-like protein production with the end goal of producing cost-effective biotherapeutic products, or therapeutic materials created utilizing recombinant DNA technology, that can be used to treat life-threatening and chronic diseases.
How being sick impacts a person’s behavior
Alex Perkins, Ph.D., Eck Family Assistant Professor in the Departments of Biological Sciences and Applied and Computational Mathematics and Statistics, and a member of the Eck Institute for Global Health, recently published a study looking at behavior of patients with one of the most common symptoms of disease: fever. Surprisingly, the impact of this common disease symptom on the mobility and contact patterns of an infected person is rarely studied and “seldom accounted for in mathematical models of transmission dynamics.”
Forcing Evolution on the Great Salt Lake Ecosystem
New research completed at the University of Notre Dame’s Environmental Research Center (UNDERC) – West indicates that as sinking brine shrimp cysts remain while many floating cysts are removed, the brine shrimp population is shifting to contain more sinking cysts.
DoD grant funds pursuit of novel insecticides to fight Zika, other diseases
A collaboration among faculty in the Eck Institute for Global Health and the Warren Family Research Center for Drug Discovery and Development is investigating new ways to kill the mosquitoes that carry the Zika virus, dengue fever, and other dangerous diseases.
Entomologist Nicole L. Achee helps write gene drives report
University of Notre Dame medical entomologist Nicole L. Achee is a member of committee convened to summarize the scientific discoveries related to gene drives and considerations for their responsible use. The National Institutes of Health (NIH) and the Foundation for the National Institutes of Health asked the National Academies of Sciences, Engineering and Medicine to convene the committee.
Using Lake Michigan turtles to measure wetland pollution
Decades of unregulated industrial waste dumping in areas of the Great Lakes have created a host of environmental and wildlife problems. Now it appears that Lake Michigan painted and snapping turtles could be a useful source for measuring the resulting pollution.
Notre Dame Research to showcase Commercialization Opportunities at BIO 2016
The University of Notre Dame will attend the 2016 BIO International Convention, which is hosted by the Biotechnology Innovation Organization (BIO) from June 6 - 9, 2016 in San Francisco. Represented Notre Dame Research groups at the event include the Harper Cancer Research Institute (HCRI), the Center for Nano Science and Technology (NDnano), as well as Technology Transfer.
Notre Dame Biology student recognized for outstanding contributions to science
Graduating Biology major, Diane Choi, is being honored with multiple academic achievement awards as the Class of 2016 prepares for graduation. Choi is the recipient of three major undergraduate awards for her work while a science student at Notre Dame. The awards include the Outstanding Biology Student Leader Award from the Department of Biological Sciences recognizing “a senior Biology major who has made outstanding contributions, through leadership and service, to advance the interests of other students in the department;”
Understanding Behavior Key to Combating Malaria
Today, April 25, is the annual World Malaria Day. This year’s theme – End Malaria for Good – seeks to build upon past successes in combatting this deadly disease, which killed over 435,000 people in 2015, and sustain this progress in order to truly “end malaria for good.” At the University of Notre Dame, Neil Lobo, a research associate professor of biological sciences and an Eck Institute for Global Health faculty member, is working to end malaria for good by focusing on the vectors that transmit the disease and how certain methods or interventions reduce malaria transmission.
Twenty-four graduate students win NSF GRFP awards
The National Science Foundation recently announced the winners of the 2016 Graduate Research Fellowship Program (GRFP), with 24 current Notre Dame students winning the prestigious award and another 17 earning honorable mention. Overall, there were 41 students recognized by the NSF. This doubles the number of Notre Dame awardees from 2015, and nearly doubles the previous Notre Dame record of 26, set last year, for total students recognized by the NSF. The NSF-GRFP recognizes and supports outstanding graduate students in NSF-supported science, technology, engineering, mathematics, and social science disciplines who are pursuing research-based degrees. The award provides a stipend, tuition support, and research funds for three years.
A tough childhood can lead to a shorter life for baboons
What is true for humans is also true for baboons: The tougher the childhood, the higher the risks of premature death later in life. Numerous studies have shown that childhood trauma can have far-reaching effects on adult health and survival; new research finds the same is true for wild baboons.
Jennifer Tank receives 2016 Ganey Award for community-based research
Jennifer Tank has received the 2016 Rodney F. Ganey, Ph.D., Community-Based Research Award for working together with Kosciusko County farmers and local conservation staff to reduce nutrient runoff in the Shatto Ditch watershed. The award is a $5,000 prize presented annually to a regular faculty member at the University of Notre Dame who has completed at least one research project that addresses a need within South Bend or the surrounding area.
With mosquito Y chromosome sequencing, researchers lay groundwork for advanced disease control
Human malaria, uniquely transmitted by a handful of anopheline mosquitoes, continues to attack nearly 200 million people and claims the lives of 600,000 each year. Africa bears the biggest burden due to its dominant vector, Anopheles gambiae. Ever since the groundbreaking Anopheles gambiae genome sequencing project was published in 2002, efforts have been underway to harness genomics for novel vector-based malaria control strategies. Nora J. Besansky, O’Hara Professor in the Department of Biological Sciences and member of the Eck Institute for Global Health at the University of Notre Dame, assembled a diverse and multinational team of scientists to crack the genetic code of the Y chromosome in malaria mosquitoes for the first time.
Indiana Watershed Initiative highlighted at White House Water Summit
A new program aimed at improving water quality in the nation’s heartland by using watershed-scale conservation to reduce nutrient runoff from farms was highlighted Tuesday (March 22) at a White House Water Summit. The program is spearheaded through a collaboration between the University of Notre Dame Environmental Change Initiative and Indiana University.
Using DNA 'fingerprinting' to understand ancestry and immunity of trees
When Europeans came to the New World in the 16th century, they brought measles and smallpox with them. Without the immunity Europeans had cultivated over the years, the native people in America quickly fell ill. Millions died as a result. Today, trees in the New World are also dying from diseases that were introduced through global trade started by the Europeans. However, trees are much more vulnerable than humans.
Bringing legendary science faculty to Notre Dame
During the one year anniversary of the death of Fr. Hesburgh, the College of Science recalls and appreciates the impact that he had on science at Notre Dame. When former Notre Dame President Father John J. Cavanaugh challenged “Where are the Catholic Salks, Oppenheimers, and Einsteins?” in a widely-read essay in the late 1950s, Father Theodore Hesburgh was already in the process of providing an answer. In both direct action, from building facilities to recruiting top scholars, and cultural transformation, from welcoming women students to asserting academic freedom, Hesburgh laid the foundations for the College of Science’s accelerating research, discovery, and mission-driven entrepreneurship in the 21st century.
New formulation of FDA-approved drug may help treat Niemann-Pick Type C disease
Niemann-Pick Type C (NPC) disease is a rare, fatal neurodegenerative disease for which there is currently no cure. NPC primarily strikes children before and during adolescence and affects one in every 150,000 children. Researchers Kasturi Haldar, the Nieuwland Professor in the Department of Biological Sciences and the Parsons-Quinn Director of the Boler-Parseghian Center for Rare and Neglected Diseases in the College of Science, and Dr. Suhail Alam and Michelle Getz in the Center for Rare and Neglected Diseases used existing FDA-approved drugs in a novel approach to treatment with promising results.
Fr. Hesburgh's impact on UNDERC
During the one year anniversary of the death of Fr. Hesburgh, the College of Science recalls and appreciates the impact that he had on science at Notre Dame. Notre Dame’s nearly 8,000-acre Land O’Lakes property in Wisconsin, originating with a 1,000-acre gift from philanthropist Martin J. Gillen in the 1930s and vastly expanded by Father Hesburgh, has been the site of high-impact gatherings hosted by Hesburgh. In 1959, a group of Northern and Southern political leaders who happened to be fishermen hammered out an agreement that became the basis of the Civil Rights Act; in 1967, a global collection of top educators issued the Land O’ Lakes Statement on Catholic higher education in America.
New avenues found for treatment of pathogen behind diseases including fasciitis, toxic shock syndrome
One bacterial pathogen is responsible for a range of diseases, from pharyngitis and impetigo to more severe diagnoses such as toxic shock syndrome and necrotizing fasciitis (flesh eating disease), a serious bacterial skin infection that spreads quickly and kills the body’s soft tissue. The pathogen, known as Group A Streptococcus, remains a global health burden with an estimated 700 million cases reported annually, and more than half a million deaths due to severe infections.