A new tool may allow researchers to see more of the physiological state of living organisms at the cellular level, according to a study by the University of Notre Dame. Published in Development, the study shows how an open-source application, created by Notre Dame researchers, can utilize two different conventional microscope images obtained at low excitation powers to create one high-resolution, three-dimensional image.
Alex Perkins, Eck Family Assistant Professor of Biological Sciences, and Sean Moore, research assistant professor of biological sciences, have been accepted to join the Vaccine Impact Modeling Consortium. The consortium “aims to deliver a more sustainable, efficient, and transparent approach to generating disease burden and vaccine impact estimates.
Sixteen faculty members from the University of Notre Dame have been awarded funding from the University’s Science of Wellness Initiative’s Catalyst Seed Grant program. Nearly 100 pre-proposals were submitted and faculty from five different colleges and schools received awards.
Guido Camargo España
Guido Camargo España, postdoctoral research associate of biological sciences, has received a Postdoctoral Training Award in Translational Research from the Indiana Clinical and Translational Sciences Institute…
Seven University of Notre Dame graduate students have successfully received fellowships from the Eck Institute for Global Health (EIGH). The EIGH Graduate Student Fellowship Program was established to support students enrolled in the Notre Dame doctorate program who have an interest in global health research.
“This fellowship program provides an opportunity for Notre Dame graduate students to work with our faculty and become more directly engaged in the fight for global health,” said Bernard Nahlen, director of the EIGH and professor of biological sciences. “I look forward to seeing how these young researchers develop their own skills and interests to contribute to better health for everyone, everywhere.”
From interdisciplinary teams to multi-institutional partnerships, collaborations in research have become commonplace. However, these interactions are often made up of siloed teams who pass information along a pipeline rather than operating cohesively. In a new study, researchers have shown how hackathons, or other crowdsourcing events, may provide a good strategy for building bridges over the traditional divides of research partnerships and accelerate scientific discovery.
Daniel Erickson, 2018 Berry Family Foundation Graduate Fellow
Daniel Erickson, graduate student of biological sciences, has been awarded a fellowship through the Advanced Diagnostics & Therapeutics (AD&T) Berry Family Foundation Graduate Fellowships for his research in the lab of Malcolm J. Fraser Jr., Rev. Julius A. Nieuwland, C.S.C. Professor of Biological Sciences, developing transgenic silkworms which produce silk that could become a low-cost source of cancer therapies.
Notre Dame Research has provided six researchers or research groups from three Colleges and Schools with awards from the Equipment and Restoration Renewal (ERR) grant program for 2018. The ERR grant program was created to assist in the restoration, replacement, and renewal of the facilities needed for faculty research at the University of Notre Dame.
People showing virtually no symptoms are likely the primary source of dengue fever, according to new research published in PLOS Pathogens. Nearly 400 million people each year are infected with dengue virus, which is transmitted through mosquitoes.
The study estimates that more than 80 percent of dengue virus infections are attributable to individuals with mild to no symptoms who do not seek treatment from a physician. The study also indicates that nearly a quarter of dengue virus transmission is the result of mosquitoes biting those already infected before the onset of symptoms. By the time those symptoms appear, the opportunity to prevent the virus from spreading has passed.
Henry Clay Conner, University of Notre Dame postdoctoral scholar, has received a Postdoctoral Training Award in Translational Research from the Indiana Clinical and Translational Sciences Institute (CTSI). The award will be used for his work in Athanasia Panopoulos’s lab.
Twenty faculty members from five of the colleges and schools have been awarded grants through the Notre Dame Research Internal Grant Program (IGP). Recipients who applied were awarded Faculty Research Support Regular Grants, Faculty Research Support Initiation Grants, Rapid Response Grants, and other internal funding.
New Notre Dame research has been used to support the Orphan Drug designation for IT-139, a compound that when used in combination with chemotherapy has proved to be significantly more effective in treating pancreatic cancer than the current standard of care. The Orphan Drug program is administered by the Food and Drug Administration (FDA) and identifies promising drugs that are intended for the treatment of rare diseases, which impact fewer than 200,000 Americans at any time, or affect more than 200,000 people but are not expected to recover the costs of developing and marketing a treatment drug. Currently, pancreatic cancer has one of the lowest cancer survival rates, with one-year and five-year rates of 20 and 7 percent, respectfully.
The Indiana State Department of Health and the Indiana Clinical and Translational Sciences Institute (CTSI) has awarded Cody J. Smith, the Elizabeth and Michael Gallagher Assistant Professor of Biological Sciences and affiliated member of the Center for Stem Cells and Regenerative Medicine, a Spinal Cord and Brain Injury Research Fund (SCBIRF) grant.
The University of Notre Dame is highlighted in a new report on the importance of scientific research to economic growth.
The study, which was conducted by The Science Coalition, identifies more than 100 companies that exist due to funding received by academic researchers from federal government agencies, including the Department of Agriculture, Department of Energy, National Institutes of Health, National Institute of Standards and Technology, and National Science Foundation.
The WHO names Tuberculosis (TB) as one of the top 10 causes of death worldwide and over 95 percent of those deaths occur in low- and middle-income countries. To improve the global health community’s understanding of TB and provide information that could help treat it, Notre Dame researchers have developed a new strain of the bacteria along with a new method to better study this deadly disease.
Although it may seem simple to calculate, snowfall cannot be well measured by simply placing a yardstick in the ground. In actuality, snow measurement is much more complicated and oftentimes the most accurate snow measurement devices are costly. However, two Notre Dame graduate students are working to improve the snow measurement process in an effective and affordable manner.
When it comes to battling disease and maintaining healthy environments, DNA sequencing can be imperative to success. At the University of Notre Dame, the Genomics and Bioinformatics Core Facility (GBCF) supports research in many areas that increasingly rely on DNA sequencing, including cancer biology, vector-borne diseases, the development of drug and antibiotic resistance, monitoring invasive species, and much more.
Malcolm Fraser Jr., the University of Notre Dame’s Rev. Julius A. Nieuwland, C.S.C., Professor of Biological Sciences, is conducting research that utilizes the silkworm caterpillar’s silk gland to conduct mammalian-like protein production with the end goal of producing cost-effective biotherapeutic products, or therapeutic materials created utilizing recombinant DNA technology, that can be used to treat life-threatening and chronic diseases.
New research completed at the University of Notre Dame’s Environmental Research Center (UNDERC) – West indicates that as sinking brine shrimp cysts remain while many floating cysts are removed, the brine shrimp population is shifting to contain more sinking cysts.
The University of Notre Dame will attend the 2016 BIO International Convention, which is hosted by the Biotechnology Innovation Organization (BIO) from June 6 - 9, 2016 in San Francisco. Represented Notre Dame Research groups at the event include the Harper Cancer Research Institute (HCRI), the Center for Nano Science and Technology (NDnano), as well as Technology Transfer.
Today, April 25, is the annual World Malaria Day. This year’s theme – End Malaria for Good – seeks to build upon past successes in combatting this deadly disease, which killed over 435,000 people in 2015, and sustain this progress in order to truly “end malaria for good.” At the University of Notre Dame, Neil Lobo, a research associate professor of biological sciences and an Eck Institute for Global Health faculty member, is working to end malaria for good by focusing on the vectors that transmit the disease and how certain methods or interventions reduce malaria transmission.
When Europeans came to the New World in the 16th century, they brought measles and smallpox with them. Without the immunity Europeans had cultivated over the years, the native people in America quickly fell ill. Millions died as a result. Today, trees in the New World are also dying from diseases that were introduced through global trade started by the Europeans. However, trees are much more vulnerable than humans.
New research from the University of Notre Dame will be used to generate maps that provide time-sensitive, mosquito-to-human ratios that determine patterns of mosquito population dynamics for the Zika virus. The model outputs will be available online to provide users with the ability to find reported cases and estimated incidences by location of the virus to improve disease transmission and prevalence forecasts, which is critical to making accurate predictions and translating results into effective public health strategies.