Molecular Understanding and Immunotherapy of Metastatic Cancer
Xin Lu, Ph.D.
John M. and Mary Jo Boler Assistant Professor
Department of Biological Sciences
Center for Rare and Neglected Diseases
Harper Cancer Research Institute
University of Notre Dame, Notre Dame, IN
Associate Member, Tumor Microenvironment and Metastasis Program
Indiana University Melvin and Bren Simon Cancer Center, 2017-Present
Phone: 574-631-6592 (office); 574-631-3960 (lab)
- John M. and Mary Jo Boler Assistant Professor, University of Notre Dame, IN 2017-Present
- Instructor, Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 2014-2016
- Jane Coffin Childs Postdoctoral Fellow. Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 2011-2014
- Jane Coffin Childs Postdoctoral Fellow. Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 2010-2011
- Ph.D. (Molecular Biology), Princeton University, Princeton, NJ 2004-2010
- B.S. (Biological Sciences), Tsinghua University, Beijing, China 2000-2004
Lab Manager/Research Assistant
Seema performs essential housekeeping experiments and lab duties, and helps maintain the smooth running of the lab.
Fang Liu, Ph.D.
Dr. Liu is building novel mouse models and study the mechanisms of VHL syndrome, a rare cancer that causes serious problems in multiple organs. She is also interested in applying her expertise in immunology to design new cancer immunotherapy approaches.
Jing Yang, Ph.D.
My research interests: I am very interested in cancer immunotherapy. Currently, cancer vaccine, immunostimulatory agents, adoptive T cell therapy and immune checkpoint blockade are the most four effective immunotherapeutic approaches used in the clinic. But there are still many types of cancer resist to them. So to study the resistant mechanism of cancer immunotherapy and find more effective multiple immunotherapies are deeply attracted me.
My hobby: I like sport. Sport makes a man healthy, makes a man wise, make people happy.
An IBMS graduate student, Sharif identifies intrinsic and extrinsic mechanisms underlying resistance to immune checkpoint blockade therapy.
Life is such a beauty, I love and admire it, it makes me crazy. An IBMS graduate student, my project now is creating a new mouse model to have a better knowledge of how the smart but bad tumor escape from immune system.
Research Visitors and Associates
Xi is a visiting graduate student from China and he identifies novel combination strategies to treat aggressive prostate cancer.
Tianhe is a visiting graduate student from China. A liked quote: "Stay hungry. Stay foolish"
William Morgenlander is a Junior Physics and Biological Sciences double major in the Glynn Family Honors Program and the Biological Sciences Honors Program. William studies the molecular underpinnings of prostate cancer using transgenic mouse models.
I am a Biology and Spanish Supplementary major from Dallas, Texas. My interests include biological and clinical research, especially cancer research. I hope to become a pediatrician one day, and would like to continue to be engaged in research.
I am interested in the molecules of life, the ways they work together to work organisms minuscule and massive, and how, when a few molecules’ working mechanisms go awry, diseases are triggered. Having gathered some experience exploring the genes of embryogenesis in C. elegans and working on the genetic engineering to express circular RNA with EGFP, I delved into cancer biology in Dr. Susan Gursky’s group through a study of the synergistic growth inhibition of AKBA and curcumin in colorectal cancer. I am currently in Dr. Xin Lu’s lab researching the mechanisms of penile cancer as well as potential treatments that stem from the discoveries.
- Shan Feng, Ph.D. Postdoc Fellow 2017-2018