May 2021, in AACR Annual Meeting 2021 (virtual week 2), Dr. Lu co-chaired with Dr. Alana Welm (University of Utah) an AACR Tumor Microenvironment Working Group Networking Session “Lab goals and culture” (see info picture below). Dr. Lu serves on the steering committee of the AACR TME Working Group.

Aacr 2021 May

April 2021, in AACR Annual Meeting 2021 (virtual week 1), Dr. Lu co-chaired with Dr. Edna Cukierman (Fox Chase Cancer Center) the mini-symposium “Identifying the Puppet Master Cells That Orchestrate Tumor Microenvironmental Players” (MS.TB06.02). This mini-symposium introduced 7 outstanding studies that highlighted the intricate cell-cell interactions in the tumor microenvironment (see a summary slide below):

Aacr 2021

April 2021, Lu lab invited two outstanding professors in the field of myeloid cells, Dr. Hongbo R. Luo (Harvard Medical School and Boston Children's Hospital) and Dr. Paulo C Rodriguez (H. Lee Moffitt Cancer Center), to give virtual seminars of the Cell Biology seminar series at Notre Dame.

Hongbo Luo     Paulo Rodriguez

April 2021, Congratulations to Loan Duong for receiving the 2021 Leiva Graduate Summer Fellowship from Institute for Precision Health at Notre Dame. This fellowship will help Loan to carry out the project on creating novel CAR-NK therapy

March 2021, Louise Medina Bengtsson received 2021 John M. and Mary Jo Boler Rare Disease Research Award from Boler-Parseghian Center for Rare and Neglected Diseases. Congratulations, Louise!

February 2021, Louise Medina Bengtsson received Undergraduate Research Program award from Eck Institute for Global Health. Congratulations, Louise!

January 2021, Our article “Effective combinatorial immunotherapy for penile squamous cell carcinoma” was featured on the Nature Communications Editors’ Highlights webpage of recent research called “Cancer”.

December 2020, Congratulations to Dr. Yun Zhao for his 2020 Early Career Investigator Award from METAvivor, a non-profit organization dedicated to increasing awareness of advanced breast cancer and equity in research and patient support. Yun is among the 12 awardees nationwide for this prestigious award.

December 2020, The Lu lab and Dr. Feng Guo’s lab at Indiana University (Bloomington) received the Collaboration in Translational Research (CTR) award from Indiana CTSI. This award will help us explore the project - A Tumor-on-a-Chip Platform for Modeling Immuno-Oncology in Prostate Cancer.

October 2020, Lu Lab received an Investigator‐Initiated Grant from American Institute for Cancer Research (AICR) to support the research on dietary modulation in cancer immunotherapy. AICR funds research that focuses on how nutrition and lifestyle affect the prevention, treatment, and survival of cancer. This work is mainly driven by Sean Murphy, a BIOS graduate student in Lu lab.

October 29, 2020, Dr. Xin Lu was invited to give a short talk on the VHL projects at the VHL Alliance 14th International Medical/Research Virtual Symposium.

October 15, 2020, Dr. Xin Lu was invited to give a virtual seminar about immunotherapy of genitourinary cancers at the 2020 Fall Seminar Series at Department of Biochemistry & Molecular Biology, Louisiana State University Health Shreveport.

2020 Fall Seminar Series

October, 2020, Lu lab invited two assistant professors, Dr. Di Zhao and Dr. Yong Cheng, to give virtual seminars of the Cell & Developmental Biology seminar series at Notre Dame.

Di Zhao
Yong Cheng


September 2020, Dr. Xin Lu is highlighted by the Mary Kay Foundation through social media:

September 2020, Congratulations to Yanting Luo and Louise for publishing our lab’s first paper that was first-authored by undergraduate students. Their work was highlighted by CRND.

August 2020, Welcome rotation students in fall 2020: Theodore Reed (BIOS), Emilija Aleksandrovic (IBMS) and Loan Duong (IBMS)!

June 2020, Dr. Lu led a panel discussion for Rare Patient Advocacy Symposium.

June 2020, Our publication in Nature Communications is highlighted by College of Science and BIOS, University of Notre Dame.

April 2020  Our publication in Nature Communications is selected by the editors as the top one of the Editors’ Highlights for Therapeutics.

April 2020  Lu lab is excited to receive grants from both National Institutes of Health (NIH)/National Cancer Institute (NCI) and Department of Defense (DOD) to support our research in prostate cancer metastasis, therapeutics and immunotherapy. These grants will decisively promote our research efforts and bring potential benefits to the patient community. We are deeply grateful to these federal grant agencies.

April 2020  Congratulations to Yanting “Raven” Luo for receiving the Paul F. Ware, M.D. Excellence in Undergraduate Research Award from the Department of Biological Sciences. This award is given to the senior who has been an exemplary undergraduate researcher and has displayed the highest level of leadership and service in the department or college, while maintaining a 3.7 GPA or higher. It is the highest honor given to a graduating senior in the department. We also wish Raven the best for her upcoming exciting graduate studies at Duke University!

April 2020  Guoqiang Liu received the Chemistry-Biochemistry-Biology Interface (CBBI) fellowship, which will support his graduate study for up to 2 years. Both Dr. Xin Lu and Dr. Matthew Webber will provide mentorship to Guoqiang. We are grateful to the CBBI Program. Congratulations, Guoqiang!

March 2020  Our publication on VHL disease (Liu et al. BMC Med Genet. 2020. PMID: 32106822.) was featured and rated as STORY OF THE WEEK by VHL Alliance, the largest organization of the VHL community.

Feb 2020   Louise Medina Bengtsson wins 2020-2021 American Association for Cancer Research AACR Undergraduate Scholar Award. This meritorious award includes complimentary registration and a $1,500 stipend each year to support participation in the AACR Annual Meeting 2020 taking place April 24-29 2020, in San Diego, CA and the AACR Annual Meeting 2021, taking place April 10-14, 2021, in Washington, DC.

Feb 2020   Yanting “Raven” Luo is highlighted on College of Science website:

Jan 2020    Lu lab is very fortunate and excited to receive the Research Scholar Grant from the American Cancer Society (ACS) to support our research in cancer immunotherapy. This grant is a significant recognition of our research efforts and tremendously promotes our research. We are deeply grateful to the support from ACS!

Dec 2019    Lu lab receives the Collaborative Project Grant from Warren Family Center for Drug Discovery & Development (WFCDD) to support Yuting Zhang’s project “High-Throughput Screening for “Killers” and “Silencers” of Polymorphonuclear Myeloid-Derived Suppressor Cells (PMN-MDSCs)”. Congratulations to Yuting!

Nov 22-25, 2019    Lu lab attended the Autumn Immunology Conference (AIC) at Chicago. Tianhe Huang and Sharif Rahmy gave oral presentations on their research progress.

Nov 14-15, 2019    Lu lab attended the Midwest Metabolism Meeting at Van Andel Institute. Sean Murphy gave an oral presentation. Yanting Luo and Louise Medina Bengtsson (both are undergraduate students) gave a poster presentation.

Aug 2019    Sharif Rahmy received Walther Cancer Foundation Interdisciplinary Interface Training Program (IITP) award, which will support him for two years. Sharif has Dr. Lu and Dr. Brian Blagg as mentors for his project on combination immunotherapy. We are grateful to Harper Cancer Research Institute and WCF for this opportunity. Congratulations, Sharif!

Aug 2019    Our lab is awarded with the Elsa U. Pardee Foundation Research Grant to support a project to develop novel inhibitors to treat prostate cancer. We are deeply grateful to the support from Elsa U. Pardee Foundation!

July 2019    Our lab is awarded with the 2019 AD&T Discovery Fund to support our collaborative project on new methods of exosome purification for immunotherapy applications. Yini Zhu leads this project.

July 2019    Our lab is awarded with the Mary Kay Foundation Cancer Research Grant to support a project titled “Novel Antibody-Drug Conjugate as Personalized Therapy for Metastatic Breast, Ovarian and Endometrial Cancers”. We express our greatest appreciation to Mary Kay Foundation!

July 2019    Welcome three iSURE students from top universities in China:Tianrui Zhang, Caiqin Wang, and Kaiwen Zhu! They will collaborate with lab members to work on exciting summer research projects.

June 2019    Yanting (Raven) Luo, junior undergraduate student with biology major in Honors Program, won SURF from Boler-Parseghian Center for Rare and Neglected Diseases to support her summer research in the lab! Congratulations!

May 2019    Sharif Rahmy presented a poster “Identifying Functional Drivers for Immunotherapy Resistance” at the IUSCC Cancer Research Day, Indianapolis. Sharif’s presentation was highlighted on the IU website:

May 2019    Midwest Tumor Microenvironment Meeting was successfully held at University of Notre Dame. The meeting hosted over 130 researchers in the tumor microenvironment field in the Midwest. Dr. Xin Lu was a co-organizer.

Apr 2019    Dr. Xin Lu invited Dr. Hua Yu to give the Department Seminar titled “STAT3: from fundamental discoveries to clinical translation”. Dr. Yu is Billy and Audrey L. Wilder Professor of Tumor Immunotherapy at City of Hope National Medical Center.

Apr 2019    Dr. Xin Lu was invited as a Grand Rounds Speaker at University of Iowa Holden Comprehensive Cancer Center, Iowa City, IA. Dr. Lu gave a talk titled “Decipher and Targeting Immunosuppressive Myeloid Cells in Cancer”.

Apr 2019    Tianhe, Sharif and Yini present their posters in the Harper Cancer Research Day.

Jan 2019    Yanting (Raven) Luo, junior undergraduate student with biology major in Honors Program, won the Research Like A Champion award from Harper Cancer Research Institute! The $12,500 research award can be used to support summer student stipends, research supplies, and travel. Congratulations!

Nov 2018    ND press coverage of Shan and Xi’s PNAS paper

Oct 2018    ND press coverage of Dr. Lu’s winning of a prestigious Susan G. Komen grant

Oct 2018    Sharif gave an oral presentation in the 2018 IBUR-IUSCC Basic Urological Research Symposium (Purdue University).

Oct 2018    Welcome Fall 2018, 2nd round rotation students: Armando Marrufo (BIOS), Samantha Golomb (BIOS) and Yuting Zhang (IBMS)!

Oct 2018    Congratulations to Sharif Rahmy for receiving the Riley Graduate Fellowship!

Aug 2018    Congratulations to Shan Feng and Xi Cheng for their PNAS paper being accepted for publication! This is the first independent research publication from the Lu group.

July 2018    Welcome Fall 2018, 1st round rotation students: Guoqiang Liu (IBMS), Meidan Wang (BIOS), and Sean Murphy (BIOS), in order of arrival.

June 2018    Welcome Karolina I. Pellot Ortiz from the University of Puerto Rico and Yuting Yang from Sichuan University (China) as undergraduate researchers in the summer! They are supported through REU and iSURE, respectively.

May 2018    Congratulations to Jacqueline Weinrich, Xiao Han and Andrew Frear to receive COS-SURF, Harper SURF, and CRND SURF, respectively! They will be working in the summer for their undergraduate research projects.

5/18/2018    Congratulations to William Morgenlander and Sam Arroyo to graduate and get bachelor degrees from University of Notre Dame! Also congratulations to William for receiving the Outstanding Biological Scientist Award from the Department of Biological Sciences!

4/1/2018     Welcome Tianhe Huang to join lab as a visiting graduate student!

3/15/2018    Welcome Yini Zhu to join lab as the second Ph.D. student from IBMS program!

12/11/2017  The lab receives an American Cancer Society Institutional Research Grant through Harper Cancer Research Institute to support the protein nitration project, carried out by Dr. Shan Feng.

9/1/2017     Welcome Xi Cheng to join lab as a visiting graduate student!

7/27/2017   Dr. Lu’s work is highlighted by Department of Defense Congressionally Directed Medical Research Programs.

7/18/2017   Dr. Shan Feng is awarded with Walther Cancer Foundation Cancer Cure Ventures Grant for his study on novel antibody-drug conjugate. His project is based on collaboration between Lu lab and the Laboratory of Dr. Matt Webber. Congratulations to Shan! We appreciate funding from Harper Cancer Research Institute/Walther Cancer Foundation.

6/1/2017     Welcome Sharif to become our first PhD graduate student! Keep good coming, Sharif! 

5/2/2017     Sam Arroyo wins 2017 Summer Undergraduate Research Fellow to support his summer research. Project title: "Myeloid Derived Suppressor Cells in Bone Metastasis of Prostate Cancer". Congratulations! More info here.

5/25/2017   Dr. Xin Lu wins 2017 Indiana CTSI Young Investigator Award. Project title "Novel Antibody-Drug Conjugates for Personalized Therapy of Lethal Prostate Cancer". Congratulations! More info here.

4/10/2017   William and Nat won the Glynn Academic Year Funding for Science Students, which will support their summer salary for research. Congratulations!

2/1/2017     Grand opening of Lu Lab!