New Notre Dame research has been used to support the Orphan Drug designation for IT-139, a compound that when used in combination with chemotherapy has proved to be significantly more effective in treating pancreatic cancer than the current standard of care. The Orphan Drug program is administered by the Food and Drug Administration (FDA) and identifies promising drugs that are intended for the treatment of rare diseases, which impact fewer than 200,000 Americans at any time, or affect more than 200,000 people but are not expected to recover the costs of developing and marketing a treatment drug. Currently, pancreatic cancer has one of the lowest cancer survival rates, with one-year and five-year rates of 20 and 7 percent, respectfully.
Recreational fishing is a longstanding American outdoor tradition, generating $25 billion annually. Whether fishing on lakes, rivers or streams; from shorelines, boats or embankments; freshwater fishing remains the most popular form of fishing, attracting more than 37 million participants last year.
While recreational fisheries are culturally and economically valuable, freshwater ecosystems are vulnerable to degradation and collapse.
University of Notre Dame biologist Michael Ferdig, Ph.D., is leading a new $11.5 million program project (P01) grant from the National Institutes of Health (NIH). Ferdig and his team at Notre Dame are partnering with researchers at the Center for Infectious Disease Research (CID Research) in Seattle and Texas Biomedical Research Institute (TBRI) to better understand the genes in the malaria parasite that are responsible for drug resistance and virulence in order to reduce and ultimately eliminate the often deadly disease.
Jennifer Tank, Galla Professor in the Department of Biological Sciences at the University of Notre Dame and director of the Environmental Change Initiative, has been announced as the president-elect of the Society for Freshwater Science (SFS).
The University of Notre Dame has received $138.1 million in research funding for fiscal year (FY) 2017, surpassing the previous record of $133.7 million set in FY 2015.
For people living in the US, the Zika epidemic of 2016 seemed to have come out of nowhere and to have now almost disappeared. Zika infections and microcephaly in newborns were daily headline news. Now where are we?
According to a new study, researchers have improved their method of tracking species by using the biological material those organisms leave behind known as environmental DNA (eDNA).
Robert P. McIntosh, a renowned ecologist and historian of ecology and wonderful husband, father and grandfather, died at 3:45 pm July 7, 2017.
He was born Sept. 24, 1920, in Milwaukee, Wis., and was a football star there at East Side High School.
He attended Lawrence College (now university) where he also played football and graduated in 1942 with a Bachelor in Science degree. He spent a summer collecting plants for Albert Fuller, Curator of Botany at the Milwaukee Public Museum.…
Scientists at the University of Notre Dame have found that exposure to just 10 minutes of light at night suppresses biting and manipulates flight behavior in the Anopheles gambiae mosquito, the major vector for transmission of malaria in Africa, according to new research published in the journal Parasites and Vectors.
Dr. Xin Lu, the John M. and Mary Jo Boler Assistant Professor of Biological Sciences, in the Boler-Parseghian Center for Rare and Neglected Diseases, has been awarded a Young Investigator Award from the Indiana Clinical and Translational Sciences Institute (CTSI).
David J. Veselik, director of undergraduate studies and associate teaching professor in the department of biological sciences, was one of three recipients of the Dockweiler Awards for the 2016–2017 academic year.
Veselik is the coordinator for the cell biology laboratory, as well as the biology club advisor. He has taught upper level cell biology labs and lectures. With his guidance, students have participated in several initiatives, including networking with the career center, vertical peer mentoring, lab shadowing and alumni mentoring.
Alyssa Lesko, fourth-year Biology graduate student, was recently selected to present her work at the 2017 Future Fellow Research Conference (FFRC) at St. Jude Children’s Research Hospital in Memphis, Tennessee. Lesko will present her work on how the loss of tumor suppressor Adenomatous Polyposis Coli (APC) and subsequently how its normal functions leads to tumorigenesis. Read more.
By understanding how they respond to toxic elements, scientists can look at how environmental changes caused by agriculture and road runoff or warming temperatures and climate change could impact populations in lakes, rivers and standing bodies of water.
The Indiana State Department of Health and the Indiana Clinical and Translational Sciences Institute (CTSI) has awarded Cody J. Smith, the Elizabeth and Michael Gallagher Assistant Professor of Biological Sciences and affiliated member of the Center for Stem Cells and Regenerative Medicine, a Spinal Cord and Brain Injury Research Fund (SCBIRF) grant.
The University of Notre Dame is highlighted in a new report on the importance of scientific research to economic growth.
The study, which was conducted by The Science Coalition, identifies more than 100 companies that exist due to funding received by academic researchers from federal government agencies, including the Department of Agriculture, Department of Energy, National Institutes of Health, National Institute of Standards and Technology, and National Science Foundation.
The National Science Foundation (NSF) recently announced the winners of the 2017 Graduate Research Fellowship Program (GRFP), with 15 current Notre Dame students, affiliates and alumni winning the prestigious award and another 18 earning honorable mention. Overall, 11 students in the Department of Biological Sciences were recognized by the NSF.
Professor Kasturi Haldar has received the 2016 Rodney F. Ganey, Ph.D., Community-Based Research Award for a project that has helped improve rare disease recognition and treatment in northern Indiana. The award is a $5,000 prize presented annually to a regular faculty member at the University of Notre Dame who has completed at least one research project that addresses a need within South Bend or the surrounding area. Haldar is a molecular cell biologist and the Rev. Julius Nieuwland Professor of Biological Sciences and Parsons-Quinn director of the Boler-Parseghian Center for Rare and Neglected Diseases at the University of Notre Dame.